The study evaluated farmers’ adoption of agricultural innovation in Oyi L.G.A of Anambra State. A multi-stage random samplingtechnique was employed to select a total of 120 respondents for the study. Primary data used were collected with the aid of questionnaire and oral interview schedule. Data were analyzed using descriptive statistics such as tables, frequency, percentage and mean score etc and inferential statistics such as regression analysis. The result showed that 58% of the farmers were females, while 84% are married, and having an average household size of 8. Furthermore, more than half (74.2%) of the farmers were between 31-60, while 71.6% of the farmers had a farm size (ha) ranging between 2-5. The result of the multiple regression analysis showed the multiple determinations (R²) was 0.616 or 61.6%, implying that 61.6% of total variation observed in the level of farmers adoption of agricultural innovation in the area was explained by the variables included in the model. The co-efficient of Age (X₁), Marital Status (X₃), and family size (X₆) bored positive coefficient, while sex (X₂), educational qualification (X₄) and farm size (X₇) showed negative coefficient. The test of hypothesis showed significance relationship between farmers’ socio-economic characteristics and their level of adoption of agricultural innovations in the area. The result further shows that fertilizer, agro-chemical and improved varieties of seeds have been adopted by the farmers to very large extent. High cost of innovation, inadequate fund, cultural and poor extension service among other were some of the factors identified that constraints adoption of innovation by the farmers. It was therefore recommended that efficient and effective extension service be introduced to farmers, local fabrication of agro-technological/ innovations based on socio-economic background of the farmers should be pursue and granting of credit facilities to farmer by government to aid them in procuring innovative technologies.